Investigating antibacterial activity of Satureja bachtiarica against coagulasenegative staphylococcus strains isolated from hospitalized patients in ICU,Tehran-Iran
نویسندگان
چکیده مقاله:
Given the inappropriate use of antibiotics and prevalence of resistant bacteria, there is urgentneed for antibacterial drugs that have fewer side effects than antibiotics. Satureja bachtiaricais a medicinal plant which had many uses in traditional medicine. In this research, the ethanolextract of leave of Satureja bachtiarica is tested on coagulase-negative staphylococcus strains.Materials and MethodsIn this experimental study, after collecting and drying the plant extract, the ethanolic extract ofthe plant was extracted by soxhelet method. Then, the antibiotic resistance pattern of coagulasenegativestaphylococcus strains to Cefoxitin, Tobramycin, Kanamycin, Amikacin, Gentamicin,was assessed. To evaluate the antibacterial activity, the minimum inhibitory concentration wasassessed by using micro dilution broth method.The results of this study showed that the antimicrobial effect of Satureja extract is concentrationdependent. The results of the antimicrobial activity of extracts, indicate that alcoholic extractin all dilutions have an antimicrobial effect on the coagulase-negative staphylococcus strains.The results show that coagulase-negative staphylococcus strains have highest resistance againstCefoxitin (0.39 mg/ml) and highest sensitivity to Amikacin (0.035 μl/ml). However, in 200 and100 mg/ml concentrations the extract has higher antibacterial effect.According to the results of this study, ethanol extracts of leave of Satureja bachtiarica hadgrowth inhibitory effect on coagulase-negative staphylococcus strains. Therefore this plant hasthe potential to be evaluated as an alternative or adjunct to antibiotics to treat coagulase-negativestaphylococcus infections.
منابع مشابه
investigating antibacterial activity of satureja bachtiarica against coagulasenegative staphylococcus strains isolated from hospitalized patients in icu,tehran-iran
given the inappropriate use of antibiotics and prevalence of resistant bacteria, there is urgentneed for antibacterial drugs that have fewer side effects than antibiotics. satureja bachtiaricais a medicinal plant which had many uses in traditional medicine. in this research, the ethanolextract of leave of satureja bachtiarica is tested on coagulase-negative staphylococcus strains.materials and ...
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عنوان ژورنال
دوره 4 شماره 2
صفحات 143- 147
تاریخ انتشار 2016-10-01
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